Price
Supports Bone Strength. Vitamin D regulates the activity of phosphorus and calciumātwo nutrients necessary for proper bone mineralization. With age, insufficient vitamin D can cause bone softening, loss of bone mineral density, and fractures. Research shows that each 10 ng/mL decrease in serum vitamin D levels is associated with a 33% increased risk of hip fracture in postmenopausal women. Vitamin K2 works together with vitamin D3 to support bone strength, as it directs calcium out of the bloodstream and into the bones, where it can increase bone mineral density. (1, 2)
Supports Cardiovascular Health. Vitamins D3 and K2 support heart health by ensuring calcium doesnāt build up (or calcify) in vascular tissue, which are leading causes of narrowed blood vessels and cardiovascular conditions. Vitamin D3 may also support healthy blood pressure and glucose metabolism. (2)
Supports Healthy Immune Function. Vitamin D plays a role in the innate immune response, which provides the first line of defense against invading pathogens. It helps to enhance the production of antimicrobial compounds and other defensive immune cells, as well as strengthen cellsā physical barrier function to keep pathogens out. In one meta-analysis, people who took vitamin D supplements had a 19% reduced risk of developing infections in the respiratory tract. (3)
Supports Healthy Mood. The therapeutic use of sunshine or light therapy for mood disorders has been used for centuries. Studies show that maintaining healthy vitamin D levels or taking vitamin D supplements significantly improves mood and mental health conditions. (4)
Supports Dental Health. A protein called osteocalcin is dependent on vitamin K2, which increases dentin productionāthe tissue under the toothās enamel. Due to its ability to take calcium from the bloodstream and deposit it into teeth, vitamin K2 can slow down the tooth loss that is common with age. (2)
References:
1. Cauley JA, Lacroix AZ, Wu L, et al. Serum 25-hydroxyvitamin D concentrations and risk for hip fractures. Ann Intern Med. 2008;149(4):242ā250. doi:10.7326/0003-4819-149-4-200808190-00005
2. Halder M, Petsophonsakul P, Akbulut AC, et al. Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease. Int J Mol Sci. 2019;20(4):896. doi:10.3390/ijms20040896
3. Martineau AR, Jolliffe DA, Hooper RL, et al. Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data. BMJ. 2017;356:i6583. doi:10.1136/bmj.i6583
4. Spedding S. Vitamin D and [mood]: a systematic review and meta-analysis comparing studies with and without biological flaws. Nutrients. 2014;6(4):1501-1518. Published 2014 Apr 11. doi:10.3390/nu6041501
Supplement Facts | ||
---|---|---|
Serving Size: 1 Capsule | ||
Servings Per Container: 30 | ||
Amount Per Serving | %DV | |
Vitamin D3 (as Cholecalciferol) | 125 mcg (5000 IU) | 625% |
BioPerineĀ® | 2.5 mg |
ā |
Vitamin K2 (as Menaquinone-7) | 100 mcg | ā |
ā Daily Value not established |